Spontaneous Cholecystocutaneous Fistula: A Case Report

Main Article Content

Pâmela de Oliveira Gonçalves Rodrigues
https://orcid.org/0009-0009-1955-6301
Gustavo Ianzer Moraes
https://orcid.org/0000-0002-5400-5267
João Pedro Valladao de Paula
Amanda Araújo Brasil Duarte
Isadora Mylius
Filipe Gianecchini Rodrigues

Abstract

Cholecystocutaneous fistula (CCF) is defined as a pathological communication between the gallbladder and/or its ducts directly with the skin. It is a rare complication of chronic calculous cholecystopathy. Its clinical presentation ranges from gastrointestinal symptoms such as nausea and vomiting, abdominal pain, jaundice, and acute pancreatitis to the drainage of biliary secretion and gallstones through the abdominal wall. The mainstay of treatment involves surgical reconstruction of the biliary anatomy. The incidence of new CCF cases appears to be decreasing due to earlier medical intervention and definitive treatments. This case report presents a patient with acute-on-chronic calculous cholecystitis who developed a CCF with externalization of a gallstone, requiring surgical management.

Article Details

How to Cite
Rodrigues, P. de O. G., Moraes, G. I., Paula, J. P. V. de, Duarte, A. A. B., Mylius, I., & Gianecchini Rodrigues, F. (2025). Spontaneous Cholecystocutaneous Fistula: A Case Report. Brazilian Journal of Case Reports, 6(1), bjcr132. https://doi.org/10.52600/2763-583X.bjcr.2026.6.1.bjcr132
Section
Clinical Case Reports
Author Biographies

Pâmela de Oliveira Gonçalves Rodrigues, Federal University of Rio Grande – FURG, Faculty of Medicine

Faculty of Medicine, Federal University of Rio Grande – FURG, Rio Grande, Rio Grande do Sul, Brazil.

Gustavo Ianzer Moraes, Faculty of Medicine, Federal University of Rio Grande – FURG

Faculty of Medicine, Federal University of Rio Grande – FURG, Rio Grande, Rio Grande do Sul, Brazil.

João Pedro Valladao de Paula, Department of General Surgery, Santa Casa de Caridade do Rio Grande – ACSCRG

Department of General Surgery, Santa Casa de Caridade do Rio Grande – ACSCRG, Rio Grande, RS, Brazil.

Amanda Araújo Brasil Duarte, Department of General Surgery, Santa Casa de Caridade do Rio Grande – ACSCRG

Department of General Surgery, Santa Casa de Caridade do Rio Grande – ACSCRG, Rio Grande, RS, Brazil.

Isadora Mylius, Faculty of Medicine, Federal University of Rio Grande – FURG

Faculty of Medicine, Federal University of Rio Grande – FURG, Rio Grande, Rio Grande do Sul, Brazil.

Filipe Gianecchini Rodrigues, Department of General Surgery, Santa Casa de Caridade do Rio Grande – ACSCRG

Department of General Surgery, Santa Casa de Caridade do Rio Grande – ACSCRG, Rio Grande, RS, Brazil.

References

Suárez EB, Navarro-Tovar F, Díaz-Barrientos CZ, Marín-Pardo EI, Hernández-Pérez E. Cholecystocutaneous fistula, an un-common pathology today. Revista de Gastroenterología de México (English Edition) [Internet]. 2023 Apr;88(2):177–9.

Alsaman MZB, Mazketly M, Ziadeh M, Aleter O, Ghazal A. Cholecystocutaneous fistula incidence, Etiology, Clinical Mani-festations, Diagnosis and treatment. A literature review. Annals of Medicine and Surgery. 2020 Nov;59:180–5.

Lofgren DH, Vasani MD S, Singzon MD V. Abdominal Wall Abscess Secondary to Cholecystocutaneous Fistula via Percu-taneous Cholecystostomy Tract. Cureus. 2019 Apr 12;11(4).

Sayed L, Sangal S, Finch G. Spontaneous Cholecystocutaneous Fistula: A Rare Presentation of Gallstones. Journal of Surgical Case Reports. 2010 Jul 1;2010(5):5–5.

Lyon C, Clark DC. Diagnosis of Acute Abdominal Pain in Older Patients. American Family Physician [Internet]. 2006 Nov 1;74(9):1537–44. Available from: https://www.aafp.org/pubs/afp/issues/2006/1101/p1537.html

Guardado-Bermúdez F, Aguilar-Jaimes A, Ardisson-Zamora FJ, Guerrero-Silva LA, Estefanie Villanueva-Rodríguez, Alondra N. Fístula colecistocutánea espontánea. Cirugía y Cirujanos. 2015 Jan 1;83(1):61–4.

Pol MM, Vyas S, Singh P, Rathore YS. Spontaneous cholecystocutaneous fistula: empirically treated for a missed diagnosis, managed by laparoscopy. BMJ Case Reports. 2019 Feb;12(2):e228138.

Malik AH, Nadeem M, Ockrim J. Complete laparoscopic management of cholecystocutaneous fistula. The Ulster Medical Journal [Internet]. 2007 Sep;76(3):166. Available from: https://pmc.ncbi.nlm.nih.gov/articles/PMC2075592/

Behrend A, Cullen ML. Cholecystocholedochal fistula, an unusual form of internal biliary fistula. Annals of surgery [Internet]. 1950 Aug;132(2):297–303. Available from: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1616562/

Birch BRP, Cox SJ. Spontaneous external biliary fistula uncomplicated by gallstones. Postgraduate Medical Journal. 1991 Apr 1;67(786):391–2.

Poudel R. Spontaneous Cholecystocutaneous Fistula: A Case Report. ResearchGate [Internet]. 2015 Apr 17;12(01):51–4. Available from: https://www.researchgate.net/publication/316276975_Spontaneous_Cholecystocutaneous_Fistula_A_Case_Report

Sulakshane S, Thakare V, Dumbre R. Consequences of gallbladder inflammation: spontaneous cholecystocutaneous fistula: a case report. International Surgery Journal. 2018 Apr 21;5(5):1974.

Rinzivillo NMA, Danna R, Leanza V, Lodato M, Marchese S, Basile F, Zanghì GN. Case Report: Spontaneous cholecystocu-taneous fistula, a rare cholethiasis complication. F1000Research [Internet]. 2017 Sep 27 ;6:1768. Available from: https://f1000research.com/articles/6-1768/v1

Tinay OE, Zaka, Mogbil Alhedaithy, Mohamad. Right hypochondrial abscess: A rare consequence of supportive cholecystitis. Annals of Medicine and Surgery. 2016 Nov 25;12:106–8.

Flora HS, Bhattacharya S. Spontaneous cholecystocutaneous fistula. HPB. 2001 Dec;3(4):279–80.

Abbey R: Spontaneous cholecystocutaneous fistula. Int J Adv Integ Med Sci. 2016, 1:196-198.

Nicholson T, Born MW, Garber E: Spontaneous cholecystocutaneous fistula presenting in the gluteal region. J Clin Gastro-enterol. 1999, 28:276-277.

Pripotnev S, Petrakos A: Cholecystocutaneous fistula after percutaneous gallbladder drainage. Case Rep Gastroenterol. 2014, 8:119-122. 10.1159/000362360

Natesan K: A rare complication of a common disease - anterior abdominal wall abscess due to spontaneous rupture of gall bladder. University Journal of Surgery and Surgical Specialities. 2017, 3:99-102. http://ejournal-tnmgrmu.ac.in/index.php/surgery/article/view/4108.

Ongso Y, Beh HN: Cholecystocutaneous abscess: a rare presentation of a common problem. Clin Med Insights Gastroenterol. 2017, 8:44-45. 10.4081/gi.2017.6899

Chopra S, Dodd III GD, Mumbower AL, et al.: Treatment of acute cholecystitis in non-critically ill patients at high surgical risk. AJR Am J Roentgenol. 2001, 176:1025-1031. 10.2214/ajr.176.4.1761025

Davis CA, Landercasper J, Gundersen LH, Lambert PJ: Effective use of percutaneous cholecystostomy in high-risk surgical patients techniques, tube management, and results. Arch Surg. 1999, 134:727-732. 10.1001/archsurg.134.7.727

Malik AH, Nadeem M, Ockrim J: Complete laparoscopic management of cholecystocutaneous fistula. Ulster Med J. 2007, 76:166-167.

Almotlaq AM: Laparoscopic management of a cholecystocutaneous fistula: a case report. J Minim Invasive Surg Sci. 2015, 4:1-3.