Efficacy of Plasma Exchange in Myasthenia Gravis Following Long COVID in a Resource-Limited Context: A Case Report

Main Article Content

Rosita Bihariesingh-Sanchit
https://orcid.org/0000-0003-0646-9507
Rakesh Bansie
https://orcid.org/0000-0002-5885-3677
Rocade Ma
Sharon Veenbergen
Dimitri Adriaan Diavatopoulos
Marien Isaäk de Jonge
Arno Nierich

Abstract

This case report describes the development of myasthenia gravis (MG) in a 71-year-old male patient with long COVID and outlines the management of an MG exacerbation. The patient exhibited significant symptoms, including fatigue, cognitive impairment, dysphagia and dysarthria. Although transient improvement was observed after treatment with pyridostigmine, the patient's condition later worsened, with marked axial and buccopharyngeal weakness. Symptom relief was finally achieved with plasmapheresis using a low-volume crossflow gravity-driven method. This case highlights the potential long-term impact of COVID-19 on autoimmune disorders such as MG and emphasizes the need for vigilance in managing post-COVID neurological complications.

Article Details

How to Cite
Bihariesingh-Sanchit, R., Bansie, R., Ma, R., Veenbergen, S., Diavatopoulos, D. A., Jonge, M. I. de, & Nierich, A. (2025). Efficacy of Plasma Exchange in Myasthenia Gravis Following Long COVID in a Resource-Limited Context: A Case Report. Brazilian Journal of Case Reports, 5(1), bjcr91. https://doi.org/10.52600/2763-583X.bjcr.2025.5.1.bjcr91
Section
Clinical Case Reports
Author Biographies

Rosita Bihariesingh-Sanchit, Department of Anaesthesiology, Academic Hospital Paramaribo

Department of Anaesthesiology, Academic Hospital Paramaribo, Republic of Suriname.

Rakesh Bansie, Department of Internal Medicine Academic Hospital Paramaribo

Department of Internal Medicine Academic Hospital Paramaribo, Republic of Suriname.

Rocade Ma, Department of Anaesthesiology, Academic Hospital Paramaribo

Department of Anaesthesiology, Academic Hospital Paramaribo, Republic of Suriname.

Sharon Veenbergen, Department of Immunology, University Medical Center Rotterdam

Department of Immunology, University Medical Center Rotterdam, Rotterdam, The Netherlands.

Dimitri Adriaan Diavatopoulos, Department of Laboratory Medicine, Laboratory of Medical Immunology, Radboud University Medical Center

Department of Laboratory Medicine, Laboratory of Medical Immunology, Radboud   University Medical Center, Nijmegen, The Netherlands.

Radboud Community for Infectious Diseases (RCI), Radboud University Medical Center, Nijmegen, The Netherlands.

Marien Isaäk de Jonge, Department of Laboratory Medicine, Laboratory of Medical Immunology

Department of Laboratory Medicine, Laboratory of Medical Immunology, Radboud  University Medical Center, Nijmegen, The Netherlands.

Radboud Community for Infectious Diseases (RCI), Radboud University Medical Center, Nijmegen, The Netherlands.

Arno Nierich, HemoClear BV

HemoClear BV, Zwolle, The Netherlands.

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