Primary Small Cell Neuroendocrine Carcinoma of the Mediastinum: Case Report of a Rare Entity

Main Article Content

Magno Giovani Zanellato
Elida Paula Benquique Ojopi
https://orcid.org/0000-0001-5824-5199
Daniela Cristina dos Santos Souza

Abstract

Small neuroendocrine carcinoma of the mediastinum (SCNCM) is a rare subtype of neuroendocrine malignancy characterized by its aggressive behavior and high rates of recurrence and metastasis. The diagnosis of this carcinoma is challenging, requiring confirmation through histopathological and immunohistochemical analysis, as well as specific imaging studies. This study reports a case of primary SCNCM that resulted in the death of a 59-year-old female patient treated at the Clinical Hospital, School of Medicine, Botucatu. The diagnostic proposal of primary small cell neuroendocrine carcinoma of the mediastinum was confirmed after a detailed analysis of the organs in an autopsy examination.

Article Details

How to Cite
Zanellato, M. G., Ojopi, E. P. B., & Souza, D. C. dos S. (2025). Primary Small Cell Neuroendocrine Carcinoma of the Mediastinum: Case Report of a Rare Entity. Brazilian Journal of Case Reports, 5(1), bjcr79. https://doi.org/10.52600/2763-583X.bjcr.2025.5.1.bjcr79
Section
Clinical Case Reports
Author Biographies

Magno Giovani Zanellato, São Paulo State University (UNESP), Medical School

São Paulo State University (UNESP), Medical School, Botucatu, São Paulo, Brazil.

Elida Paula Benquique Ojopi, Clinical Hospital, Botucatu School of Medicine

Clinical Hospital, Botucatu School of Medicine, Botucatu, São Paulo, Brazil.

Daniela Cristina dos Santos Souza, São Paulo State University (UNESP), Medical School

São Paulo State University (UNESP), Medical School, Botucatu, São Paulo, Brazil.

Clinical Hospital, Botucatu School of Medicine, Botucatu, São Paulo, Brazil.

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