Bone marrow necrosis caused by Acute Leukemia: a case report

Jandir Mendonça  Nicacio; Michelle Ribeiro Viana Taveira; Anna Caroline Figueiredo Falcão de Amorim; Leonardo Fernandes e Santana

doi:10.52600/2763-583X.bjcr.2022.2.2.24-30

PDF

Published: Mar 18, 2022

DOI: https://doi.org/10.52600/2763-583X.bjcr.2022.2.2.24-30

Keywords:

Lymphoblastic Leukemia, Bone Marrow, Necrosis

Jandir Mendonça Nicacio

Preceptor of the Internal Medicine Residency at the University Hospital of the Universidade Federal do Vale do São Francisco (UNIVASF)

https://orcid.org/0000-0001-9139-2414

Michelle Ribeiro Viana Taveira

Hospital Dom Tomás

Anna Caroline Figueiredo Falcão de Amorim

Pediatric Oncologist at Hospital Dom Tomás

Leonardo Fernandes e Santana

Internal Medicine Residency at the University Hospital of the Universidade Federal do Vale do São Francisco (UNIVASF)

Abstract

Bone marrow necrosis (BMN) is an entity resulting from an infarction of the bone marrow stroma without involvement of the cortical bone. It is a serious complication which is associated with malignant neoplasia(among other diseases), with acute leukemia being the most described cause. From these cases, about 18% are acute lymphoblastic leukemia (ALL), affecting less than 0.5% of patients with this pathology. Its histopathology is marked by the depletion of fat cells in an eosinophilic medium with the presence of amorphous material in at least 50% of the sample. The presence of BMNs in acute leukemia suggests a worse prognosis and lower remission rates. This observational study describes a case report of BMN caused by acute leukemia, with the databeing obtained from the electronic medical record in the UNIVASF University Hospital System (UH).

How to Cite

Nicacio, J. M. ., Taveira, M. R. V., Amorim, A. C. F. F. de, & Santana, L. F. e. (2022). Bone marrow necrosis caused by Acute Leukemia: a case report. Brazilian Journal of Case Reports, 2(2), 24–30. https://doi.org/10.52600/2763-583X.bjcr.2022.2.2.24-30

Issue

Vol. 2 No. 2 (2022): April/June - 2022

Section

Clinical Case Reports

This work is licensed under a Creative Commons Attribution 4.0 International License.

Author Biographies

Jandir Mendonça Nicacio, Preceptor of the Internal Medicine Residency at the University Hospital of the Universidade Federal do Vale do São Francisco (UNIVASF)

Preceptor of the Internal Medicine Residency at the University Hospital of the Universidade Federal do Vale do São Francisco (UNIVASF), Petrolina, Pernambuco, Brazil.

Professor of Hematological Diseases and Oncology at Universidade Federal do Vale do São Francisco (UNIVASF), Petrolina, Pernambuco, Brazil.

Michelle Ribeiro Viana Taveira, Hospital Dom Tomás

Pediatric Oncologist at Hospital Dom Tomás, Petrolina, PE.

Preceptor at the Medical Residency in Pediatrics at Hospital Dom Malan, Petrolina, PE.

Professor of Pediatrics at Universidade Federal do Vale do São Francisco (UNIVASF), Petrolina, Pernambuco, Brazil

Anna Caroline Figueiredo Falcão de Amorim, Pediatric Oncologist at Hospital Dom Tomás

Pediatric Oncologist at Hospital Dom Tomás, Petrolina, PE.

Leonardo Fernandes e Santana, Internal Medicine Residency at the University Hospital of the Universidade Federal do Vale do São Francisco (UNIVASF)

Internal Medicine Residency at the University Hospital of the Universidade Federal do Vale do São Francisco (UNIVASF), Petrolina, Pernambuco, Brazil.

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