Management of breast cancer patients leptomeningeal carcinomatosis: experience with Ommaya catheter

Main Article Content

Felipe de Lacerda Pereira
https://orcid.org/0000-0001-8590-4612
Letícia Assad Maia Sandoval
https://orcid.org/0000-0002-6916-2249
Luiza Bernardes Ferreira
https://orcid.org/0000-0002-0527-1622
Ana Paula Teixeira Leite
https://orcid.org/0000-0001-7354-885X
Juliana Moreira Batista
https://orcid.org/0000-0001-9852-9292
Tatiana Strava Corrêa
https://orcid.org/0000-0003-1858-6583

Abstract

Leptomeningeal Carcinomatosis is a recurrent complication in different types of tumors with systemic involvement, especially breast cancers. Thus, given the different forms of treatment for this disease, this article presents the effectiveness of using Ommaya catheter as a way of administering chemotherapy. Two cases of breast cancer were studied and their therapeutic evolution reported. Despite the poor prognosis associated with meningeal carcinomatosis, these cases had a disease response and control for a longer period than the expected median.

Article Details

How to Cite
de Lacerda Pereira, F., Assad Maia Sandoval, L., Bernardes Ferreira, L., Teixeira Leite, A. P., Moreira Batista, J., & Strava Corrêa, T. (2021). Management of breast cancer patients leptomeningeal carcinomatosis: experience with Ommaya catheter. Brazilian Journal of Case Reports, 1(3), 125–130. https://doi.org/10.52600/2763-583X.bjcr.2021.1.3.125-130
Section
Clinical Case Reports
Author Biographies

Felipe de Lacerda Pereira , Medical School, University Center of Brasília

Medical School, University Center of Brasília, Federal District, DF, Brazil.

Letícia Assad Maia Sandoval, Medical School, University of Brasília

Medical School, University of Brasília, Federal District, DF, Brazil.

Luiza Bernardes Ferreira, Medical School, Catholic University of Brasília

Medical School, Catholic University of Brasília, Federal District, DF, Brazil.

Ana Paula Teixeira Leite, Medical School, Catholic University of Brasília

Medical School, Catholic University of Brasília, Federal District, DF, Brazil.

Juliana Moreira Batista, Medical School, Catholic University of Brasília

Medical School, Catholic University of Brasília, Federal District, DF, Brazil.

Tatiana Strava Corrêa, Medical Oncology, Sírio-Libanês Hospital

Medical Oncology, Sírio-Libanês Hospital, Federal District, DF, Brazil.

References

Katz A, Marques R, Novis Y, Rocha V, Costa FP, Fernandes GS, Ferrari CLS, Hoff PMG. Oncologia Clínica: Terapia Baseada em Evidências [2.ed.]. SÃO PAULO: SBSHSL - Sociedade Beneficiente de Senhoras Hospital Sírio-Libanês, 2014:624.

Martins SJ, Azevedo CRAS, Chinen LTD, Peterlevitz MA, Gimenes DL. Meningeal Carcinomatosis in Solid Tumors. 2011;69(6):973–80. [3] Gleissner B, Chamberlain MC. Neoplastic meningitis. Lancet Neurol. 2006 May;5(5):443-52. doi: 10.1016/S1474-4422(06)70443-4.

Grossman SA, Krabak MJ. Leptomeningeal carcinomatosis. Cancer Treat Rev. 1999 Apr;25(2):103-19. doi: 10.1053/ctrv.1999.0119.

Montes de Oca Delgado M, Cacho Díaz B, Santos Zambrano J, Guerrero Juárez V, López Martínez MS, Castro Martínez E, Avendaño Méndez-Padilla J, Mejía Pérez S, Reyes Moreno I, Gutiérrez Aceves A, González Aguilar A. The Comparative Treatment of Intraventricular Chemotherapy by Ommaya Reservoir vs. Lumbar Puncture in Patients With Leptomeningeal Carcinomatosis. Front Oncol. 2018 Nov 20;8:509. doi: 10.3389/fonc.2018.00509.

Gwak HS, Lee SH, Park WS, Shin SH, Yoo H, Lee SH. Recent Advancements of Treatment for Leptomeningeal Carcinomatosis. J Korean Neurosurg Soc. 2015 Jul;58(1):1-8. doi: 10.3340/jkns.2015.58.1.1.

Sandberg DI, Bilsky MH, Souweidane MM, Bzdil J, Gutin PH. Ommaya reservoirs for the treatment of leptomeningeal metastases. Neurosurgery. 2000 Jul;47(1):49-54; discussion 54-5. doi: 10.1097/00006123-200007000-00011.

Wen PY, Plotkin SR. Neurologic complications of cancer chemotherapy. UpToDate, 2006. Available at: www.uptodate.com. Accessed 27 April 2006.https://www.uptodate.com/contents/overview-of-neurologic-complications-of-conventional-non-platinum-cancer-chemotherapy

Kim H, Lee EM. A Retrospective Analysis of the Clinical Outcomes of Leptomeningeal Metastasis in Patients with Solid Tumors. Brain Tumor Res Treat. 2018 Oct;6(2):54-59. doi: 10.14791/btrt.2018.6.e12.