Management of breast cancer patients leptomeningeal carcinomatosis: experience with Ommaya catheter
Main Article Content
Abstract
Leptomeningeal Carcinomatosis is a recurrent complication in different types of tumors with systemic involvement, especially breast cancers. Thus, given the different forms of treatment for this disease, this article presents the effectiveness of using Ommaya catheter as a way of administering chemotherapy. Two cases of breast cancer were studied and their therapeutic evolution reported. Despite the poor prognosis associated with meningeal carcinomatosis, these cases had a disease response and control for a longer period than the expected median.
Article Details
This work is licensed under a Creative Commons Attribution 4.0 International License.
References
Katz A, Marques R, Novis Y, Rocha V, Costa FP, Fernandes GS, Ferrari CLS, Hoff PMG. Oncologia Clínica: Terapia Baseada em Evidências [2.ed.]. SÃO PAULO: SBSHSL - Sociedade Beneficiente de Senhoras Hospital Sírio-Libanês, 2014:624.
Martins SJ, Azevedo CRAS, Chinen LTD, Peterlevitz MA, Gimenes DL. Meningeal Carcinomatosis in Solid Tumors. 2011;69(6):973–80. [3] Gleissner B, Chamberlain MC. Neoplastic meningitis. Lancet Neurol. 2006 May;5(5):443-52. doi: 10.1016/S1474-4422(06)70443-4.
Grossman SA, Krabak MJ. Leptomeningeal carcinomatosis. Cancer Treat Rev. 1999 Apr;25(2):103-19. doi: 10.1053/ctrv.1999.0119.
Montes de Oca Delgado M, Cacho Díaz B, Santos Zambrano J, Guerrero Juárez V, López Martínez MS, Castro Martínez E, Avendaño Méndez-Padilla J, Mejía Pérez S, Reyes Moreno I, Gutiérrez Aceves A, González Aguilar A. The Comparative Treatment of Intraventricular Chemotherapy by Ommaya Reservoir vs. Lumbar Puncture in Patients With Leptomeningeal Carcinomatosis. Front Oncol. 2018 Nov 20;8:509. doi: 10.3389/fonc.2018.00509.
Gwak HS, Lee SH, Park WS, Shin SH, Yoo H, Lee SH. Recent Advancements of Treatment for Leptomeningeal Carcinomatosis. J Korean Neurosurg Soc. 2015 Jul;58(1):1-8. doi: 10.3340/jkns.2015.58.1.1.
Sandberg DI, Bilsky MH, Souweidane MM, Bzdil J, Gutin PH. Ommaya reservoirs for the treatment of leptomeningeal metastases. Neurosurgery. 2000 Jul;47(1):49-54; discussion 54-5. doi: 10.1097/00006123-200007000-00011.
Wen PY, Plotkin SR. Neurologic complications of cancer chemotherapy. UpToDate, 2006. Available at: www.uptodate.com. Accessed 27 April 2006.https://www.uptodate.com/contents/overview-of-neurologic-complications-of-conventional-non-platinum-cancer-chemotherapy
Kim H, Lee EM. A Retrospective Analysis of the Clinical Outcomes of Leptomeningeal Metastasis in Patients with Solid Tumors. Brain Tumor Res Treat. 2018 Oct;6(2):54-59. doi: 10.14791/btrt.2018.6.e12.