Bisphosphonate-induced osteonecrosis of the jaws: a literature review

Main Article Content

Nayane de Andrade Teófilo
Caio Denardin
Thiago Quirino Mota da Silva
Túlio Garcia Margute
Andrei Rabenschlag Rossato
Max Soares Maione
Tiago Garcia Margute
Igor Fonseca dos Santos

Abstract

Bisphosphonates are widely used, whether in osteoporosis or malignant bone disorders. Therefore, it is necessary that there is sufficient knowledge about the adverse effects of this drug, especially in relation to Osteonecrosis of the Jaws Developed by Bisphosphonates, which is a pathology generated in the gnathic bones. So, the following question was asked in the research problem: What is the current situation regarding the use of bisphosphonates and the onset of osteonecrosis of the jaw? Searches were carried out on digital library websites in search of articles and research in books by renowned authors. Inclusion and exclusion criteria for articles found were defined. The verification of each article was carried out so that it could have perspective and follow-up on the subject discussed. The following databases were used: PUBMED, BIREME and LILACS, and SCIELO between the years 2007 to 2019. It was concluded then that Bisphosphonates play a very important role as a cause of osteonecrosis of the jaws, where the prognosis will be worse if the patient is treated with intravenous rather than oral types.

Article Details

How to Cite
Teófilo , N. de A. ., Denardin, C., da Silva , T. Q. M. ., Margute , T. G. ., Rossato , A. R. ., Maione, M. S. ., Margute , T. G. ., & dos Santos , I. F. . (2021). Bisphosphonate-induced osteonecrosis of the jaws: a literature review. Brazilian Journal of Case Reports, 1(4), 190–198. https://doi.org/10.52600/2763-583X.bjcr.2021.1.4.190-198
Section
Health Review
Author Biographies

Nayane de Andrade Teófilo , Centro Universitário Luterano de Palmas (CEULP-ULBRA)

Centro Universitário Luterano de Palmas (CEULP-ULBRA), Palmas, TO, Brazil

Caio Denardin, Department of Periodontics, Centro Universitário Tocantinense Presidente Antônio Carlos, ITPAC

Department of Periodontics, Centro Universitário Tocantinense Presidente Antônio Carlos, ITPAC, TO, Araguaína, Brazil.

Thiago Quirino Mota da Silva , Department of Implantology, CEUMA University

Department of Implantology, CEUMA University, MA, São Luis, Brazil.

Túlio Garcia Margute , Department of Phrostodontics, Faculty of the Center West of São Paulo

Department of Phrostodontics, Faculty of the Center West of São Paulo, FACOP, SP, Bauru, Brazil.

Andrei Rabenschlag Rossato , Department of Implantology, São Leopoldo Mandic

Department of Implantology, São Leopoldo Mandic, SP, Campinas, Brazil.

Max Soares Maione, Department of Implantology, CEUMA University

Department of Implantology, CEUMA University, MA, São Luis, Brazil.

Tiago Garcia Margute , Department of Implantology, FACOP

Department of Implantology, FACOP, SP, Bauru, Brazil.

Igor Fonseca dos Santos , Department of Medicine and Dentistry, UNIRG, Paraíso do Tocantins, CEULP-ULBRA, IOA

Department of Medicine and Dentistry, UNIRG, Paraíso do Tocantins, CEULP-ULBRA, IOA, Palmas, TO Tocantins, TO, Brazil.

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