Fetal Dilated Myocardiopathy – Case Report: Association with a heterozygous mutation in MYH7 gene

Main Article Content

Danielle Negri de Souza Lopes
Fernanda Saraiva Bueno
Marcia Cristina de Azevedo Gomes
Sergio Ramos
Fernando Freitas Martins
Cassio Luiz de Carvalho Serão
Maria Elisabeth Lopes Moreira
José Maria de Andrade Lopes
https://orcid.org/0000-0002-2356-4656

Abstract

We report a case of dilated myocardiopathy with ascites and cardiac dysfunction detected at 20 weeks’ gestation. Baby was born at 33 weeks and 6 days, weighing 2530g, delivered by cesarean section and admitted to NICU. Postnatal echocardiography confirmed biventricular severe dysfunction, need of ventilatory support, vasoactive drugs, and prostaglandins. He was investigated for metabolic, infectious, and viral diseases with no positive results. After 6 weeks, he was transferred to a transplant center. Exome sequence showed a heterozygous mutation in the MYH7 gene (OMIN-160760.0028).

Article Details

How to Cite
Lopes, D. N. de S., Bueno, F. S., Gomes, M. C. de A., Ramos, S., Martins, F. F., Serão, C. L. de C., Moreira, M. E. L., & Lopes, J. M. de A. (2024). Fetal Dilated Myocardiopathy – Case Report: Association with a heterozygous mutation in MYH7 gene. Brazilian Journal of Case Reports, 4(4), 57–60. https://doi.org/10.52600/2763-583X.bjcr.2024.4.4.57-60
Section
Clinical Case Reports
Author Biographies

Danielle Negri de Souza Lopes, Neonatal Intensive Care Unit, Perinatal Maternity Hospital

Neonatal Intensive Care Unit, Perinatal Maternity Hospital, Rio de Janeiro, RJ, Brazil.

Fernanda Saraiva Bueno, Neonatal Intensive Care Unit, Perinatal Maternity Hospital

Neonatal Intensive Care Unit, Perinatal Maternity Hospital, Rio de Janeiro, RJ, Brazil.

Marcia Cristina de Azevedo Gomes, Neonatal Intensive Care Unit, Perinatal Maternity Hospital

Neonatal Intensive Care Unit, Perinatal Maternity Hospital, Rio de Janeiro, RJ, Brazil.

Sergio Ramos, Neonatal Intensive Care Unit, Perinatal Maternity Hospital

Neonatal Intensive Care Unit, Perinatal Maternity Hospital, Rio de Janeiro, RJ, Brazil.

Fernando Freitas Martins, Neonatal Intensive Care Unit, Perinatal Maternity Hospi

Neonatal Intensive Care Unit, Perinatal Maternity Hospital, Rio de Janeiro, RJ, Brazil.

Cassio Luiz de Carvalho Serão, Genetics - Medical Faculty Petropolis

Genetics - Medical Faculty Petropolis, RJ, Brazil.

Maria Elisabeth Lopes Moreira, Neonatology of National Institute of Women’s and Child’s Health Fernandes Figueira

Neonatology of National Institute of Women’s and Child’s Health Fernandes Figueira, Fiocruz, RJ, Brazil.

José Maria de Andrade Lopes, Neonatology of National Institute of Women’s and Child’s Health Fernandes Figueira

Neonatology of National Institute of Women’s and Child’s Health Fernandes Figueira, Fiocruz, RJ, Brazil.

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