Carcinoma Ex Pleomorphic Adenoma - Report of a Rare Case in the Cheek Mucosa
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Abstract
Carcinoma ex pleomorphic adenoma (CEPA) is a malignization of pleomorphic adenoma and often evolves silently. Its occurrence is rare and predominantly affects the major salivary glands, with the palate being the most common intraoral location. It is recognized as a condition with difficult clinical and pathological diagnosis, and histopathology remains the gold standard for definitive diagnosis. This study presents a primary CEPA in the buccal mucosa identified in a 69-year-old female patient. Less invasive tumors are associated with good prognosis; therefore, early recognition is important as they can become more aggressive, leading to more comprehensive therapies and reserved prognoses.
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